Is it safe to take Metoprolol at night when my heart rate rests at an average of 65bpm? Doesn’t Metoprolol slow my heart rate? I am taking meds for PVC’s only.

Yes it is safe to take Metoprolol at night. Often it is preferred because one of the side effects is fatigue and it is less likely to make you tired if you are sleeping. You are taking this to suppress your extra beats or palpitations and it should help with those.